Nuclear Spin Relaxation Parameters of MRI Contrast Agents – Insight from Quantum Mechanical Calculations
نویسندگان
چکیده
منابع مشابه
Nuclear spin relaxation induced by a mechanical resonator.
We report on measurements of the spin lifetime of nuclear spins strongly coupled to a micromechanical cantilever as used in magnetic resonance force microscopy. We find that the rotating-frame correlation time of the statistical nuclear polarization is set by the magnetomechanical noise originating from the thermal motion of the cantilever. Evidence is based on the effect of three parameters: (...
متن کاملPolycatechol Nanoparticle MRI Contrast Agents.
Amphiphilic triblock copolymers containing Fe(III) -catecholate complexes formulated as spherical- or cylindrical-shaped micellar nanoparticles (SMN and CMN, respectively) are described as new T1-weighted agents with high relaxivity, low cytotoxicity, and long-term stability in biological fluids. Relaxivities of both SMN and CMN exceed those of established gadolinium chelates across a wide rang...
متن کاملContrast agents for hepatic MRI
Liver specific contrast media (LSCM) can be subdivided according to different modalities of hepatic distribution: exclusive distribution to the hepatocellular compartment can be obtained using CM which accumulate within the hepatocytes after slow infusion; other CM demonstrate combined perfusion and hepatocyte-selective properties, with an initial distribution to the vascular-interstitial compa...
متن کاملMRI contrast from relaxation along a fictitious field (RAFF).
A new method to measure rotating frame relaxation and to create contrast for MRI is introduced. The technique exploits relaxation along a fictitious field (RAFF) generated by amplitude- and frequency-modulated irradiation in a subadiabatic condition. Here, RAFF is demonstrated using a radiofrequency pulse based on sine and cosine amplitude and frequency modulations of equal amplitudes, which gi...
متن کاملDevelopment of 153Sm-DTPA-SPION as a theranostic dual contrast agents in SPECT/MRI
Objective(s): This study describes the preparation, biodistribution of 153Sm-DTPA-SPION after intravenous injection in rats. Materials and Methods: The chelator DTPA dianhydride was conjugated to SPION using a small modification of the well-known cyclic anhydride method. Conjugation was done at a 1: 4 (SPION: ccDTPA) molar ratio. Conjugation reaction was purified with magnetic assorting column...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Inorganic Chemistry
سال: 2007
ISSN: 1434-1948,1099-0682
DOI: 10.1002/ejic.200701013